Anti-Cancer Agents – Chemotherapy, Targeted Therapy & Immunotherapy

Introduction

Cancer therapy requires a multi-modal approach, including traditional chemotherapy, targeted therapies, and modern immuno-oncology agents. Nirvana Pharma’s oncology range covers alkylating agents, antimetabolites, taxanes, monoclonal antibodies, TKIs, and checkpoint inhibitors, ensuring a broad spectrum of options for clinicians.


🔹 Traditional Cytotoxic Chemotherapy

Alkylating Agents

Drug Strengths / Forms
Cyclophosphamide Tab: 50 mg; Inj: 200 mg, 500 mg, 1 g vial
Ifosfamide Inj: 1 g, 2 g vial
Busulfan Tab: 2 mg; Inj: 60 mg/10 mL

Platinum Compounds

Drug Strengths / Forms
Cisplatin Inj: 10 mg, 50 mg vial
Carboplatin Inj: 150 mg, 450 mg vial
Oxaliplatin Inj: 50 mg, 100 mg vial

Antimetabolites

Drug Strengths / Forms
Methotrexate Tab: 2.5 mg, 10 mg; Inj: 50 mg/2 mL, 500 mg vial
5-Fluorouracil (5-FU) Inj: 250 mg/5 mL, 500 mg/10 mL
Capecitabine Tab: 150 mg, 500 mg
Cytarabine Inj: 100 mg, 500 mg, 1 g vial

Anthracyclines

Drug Strengths / Forms
Doxorubicin Inj: 10 mg, 50 mg vial
Epirubicin Inj: 10 mg, 50 mg vial
Daunorubicin Inj: 20 mg, 50 mg vial

Vinca Alkaloids

Drug Strengths / Forms
Vincristine Inj: 1 mg, 2 mg vial
Vinblastine Inj: 10 mg vial
Vinorelbine Inj: 10 mg/mL, 50 mg/5 mL

Taxanes

Drug Strengths / Forms
Paclitaxel Inj: 30 mg/5 mL, 100 mg/16.7 mL
Docetaxel Inj: 20 mg/1 mL, 80 mg/4 mL, 160 mg/8 mL

Topoisomerase Inhibitors

Drug Strengths / Forms
Etoposide Cap: 50 mg, 100 mg; Inj: 100 mg/5 mL
Irinotecan Inj: 100 mg/5 mL
Topotecan Cap: 0.25 mg, 1 mg; Inj: 4 mg vial

🔹 Targeted Therapy

Tyrosine Kinase Inhibitors (TKIs)

Drug Strengths / Forms
Imatinib Tab: 100 mg, 400 mg
Dasatinib Tab: 20 mg, 50 mg, 70 mg, 100 mg
Nilotinib Cap: 150 mg, 200 mg
Erlotinib Tab: 25 mg, 100 mg, 150 mg
Gefitinib Tab: 250 mg
Sorafenib Tab: 200 mg
Sunitinib Cap: 12.5 mg, 25 mg, 50 mg
Lapatinib Tab: 250 mg
Osimertinib Tab: 40 mg, 80 mg

mTOR Inhibitors

Drug Strengths / Forms
Everolimus Tab: 5 mg, 10 mg
Temsirolimus Inj: 25 mg/mL

Monoclonal Antibodies (MoAbs)

Drug Strengths / Forms
Trastuzumab Inj: 150 mg, 420 mg vial
Bevacizumab Inj: 100 mg/4 mL, 400 mg/16 mL
Rituximab Inj: 100 mg/10 mL, 500 mg/50 mL
Cetuximab Inj: 100 mg/50 mL
Pertuzumab Inj: 420 mg/14 mL

🔹 Immunotherapy

Immune Checkpoint Inhibitors

Drug Strengths / Forms
Nivolumab Inj: 40 mg/4 mL, 100 mg/10 mL
Pembrolizumab Inj: 100 mg/4 mL
Drug Strengths / Forms
Atezolizumab Inj: 1200 mg/20 mL
Durvalumab Inj: 500 mg/10 mL
Avelumab Inj: 200 mg/10 mL

CTLA-4 Inhibitors

Drug Strengths / Forms
Ipilimumab Inj: 50 mg/10 mL, 200 mg/40 mL

Cytokine Therapy (Older Immunotherapy)

Drug Strengths / Forms
Interleukin-2 (Aldesleukin) Inj: 1.3 mg vial
Interferon-alpha Inj: 3 MIU, 5 MIU, 18 MIU vials

Oncolytic Virus Therapy (Emerging)

Drug Strengths / Forms
Talimogene laherparepvec (T-VEC) Inj: 100 million PFU/mL

Closing Note

From traditional chemotherapy to precision-targeted TKIs and monoclonal antibodies, Nirvana Pharma delivers a comprehensive oncology portfolio. With the addition of checkpoint inhibitors and emerging immunotherapies, our goal is to ensure clinicians have access to life-saving cancer treatments across multiple tumor types.

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